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Crohn's Disease

Crohn's disease has historically been considered more common in white populations, but rates among Black Americans are rising and are now similar to or approaching those of other groups. However, Black patients face significant disparities in care — they are more likely to be diagnosed at a later stage, less likely to be referred to a gastroenterologist, and less likely to receive advanced therapies such as biologics. Black patients also experience higher rates of complications and surgery, often due to delayed diagnosis and unequal access to specialist care.

Overview

Crohn's disease is a type of inflammatory bowel disease (IBD) that causes chronic inflammation of the digestive tract. It can affect any part of the tract from the mouth to the anus, but most commonly involves the small intestine and the beginning of the large intestine. The inflammation often spreads deep into the layers of affected bowel tissue, causing abdominal pain, severe diarrhea, fatigue, weight loss, and malnutrition. Crohn's is a lifelong condition with periods of flare-ups and remission, and there is currently no cure.

Common Symptoms
  • Persistent diarrhea
  • Abdominal pain and cramping, often in the lower right area
  • Blood in the stool
  • Unexplained weight loss
  • Fatigue and low energy
  • Reduced appetite
  • Mouth sores
  • Joint pain or skin rashes in some cases
  • Fever during flare-ups
Risk Factors in Our Community
  • Family history of Crohn's disease or inflammatory bowel disease
  • Cigarette smoking, which worsens disease severity
  • Age — most commonly diagnosed between ages 15 and 35
  • Diet high in processed foods and low in fiber
  • Certain medications such as NSAIDs that can trigger flare-ups
  • Environmental factors and changes in gut bacteria
  • Living in urban or industrialized areas
  • Ashkenazi Jewish ancestry, though it affects all groups

Clinical Trials

Explore clinical trials seeking participants for Crohn's Disease research.

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Medical Disclaimer

This information is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare provider for diagnosis and treatment.